AC410 (AC-410; AC430; AC-430) is a novel and potent inhibitor of Janus kinase 2 (JAK2) with antiinflammatory effects. It inhibits JAK2 with a Kd of 0.18 nM and is selective for JAK2, with a Kd of 2.5 nM for JAK1 and 5nM for JAK3. Phase I for the treatment of Autoimmune disorders and Inflammation is on-going.

纯度：≥98%

CAS：1361415-84-0