| CAS NO: | 165682-93-9 |
| 规格: | ≥98% |
| 包装 | 价格(元) |
| 5mg | 电议 |
| 10mg | 电议 |
| 25mg | 电议 |
| 50mg | 电议 |
| 100mg | 电议 |
| 250mg | 电议 |
| 500mg | 电议 |
| Molecular Weight (MW) | 282.75 |
|---|---|
| Formula | C12H11ClN2O2S |
| CAS No. | 165682-93-9 |
| Storage | -20℃ for 3 years in powder form |
| -80℃ for 2 years in solvent | |
| Solubility (In vitro) | DMSO: 56 mg/mL (198.1 mM) |
| Water: <1 mg/mL | |
| Ethanol: 20 mg/mL (70.7 mM) | |
| Other info | Chemical Name: ethyl 2-((4-chlorophenyl)amino)thiazole-4-carboxylate InChi Key: ULUBAPWNHROTEU-UHFFFAOYSA-N InChi Code: InChI=1S/C12H11ClN2O2S/c1-2-17-11(16)10-7-18-12(15-10)14-9-5-3-8(13)4-6-9/h3-7H,2H2,1H3,(H,14,15) SMILES Code: O=C(C1=CSC(NC2=CC=C(Cl)C=C2)=N1)OCC |
| Synonyms | O4I2; O-4I2; O4I-2; O-4I 2; O-4I2; O-4I-2; O4-I-2 |
| In Vitro | In vitro activity: O4I2 activates Oct3/4 expression in HEK293 and embryonal NCCIT cells, and also in Oct-deficient HeLa and terminally differentiated human fibroblasts, and also induces other pluripotency-associated genes such as Lin28 and Nanog. |
|---|---|
| In Vivo | |
| Animal model | |
| Formulation & Dosage | |
| References | J Med Chem. 2015 Aug 13;58(15):5742-50. |
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