Acitazanolast (MTCC, WP-871), active metabolite of tazanolast, is an anti-allergic drug candidate. Aerosol WP871 (0.01 and 0.033%) inhibited the antigen-induced bronchoconstriction to some extent in a dose-dependent fashion, but high-dose WP871 (0.1%) inhalation itself produced a non-specific bronchoconstriction. Aerosol WP871 does not antagonize SRS-A, but inhibits synthesis and/or release of SRS-A and has some non-specific bronchoconstrictive effect in high concentration.

纯度：≥98%

CAS：114607-46-4