ZK216348 is a selective nonsteroidal glucocorticoid receptor (GR) agonist for the treatment of experimental colitis with IC50 of 20, 20, and 80 nM for GR, Progesterone (PR) and Mineralocorticoid (MR) receptors respectively. (ZK 216348 shows anti-inflammatory activity comparable to prednisolone for both systemic and topical application. References: Reuter KC, Loitsch SM, Dignass AU, Steinhilber D, Stein J. Selective non-steroidal glucocorticoid receptor agonists attenuate inflammation but do not impair intestinal epithelial cell restitution in vitro. PLoS One. 2012;7(1):e29756. doi: 10.1371/journal.pone.0029756. Epub 2012 Jan 25. PubMed PMID: 22295067; PubMed Central PMCID: PMC3266253.

纯度：≥98%

CAS：669073-68-1