Z-Ile-Leu-al is a cell-permeable, reversible inhibitor of γ-secretase. It acts by reducing amyloid β (Aβ)-production by blocking γ-secretase activity in vitro. References: Séveno C, Loussouarn D, Bréchet S, Campone M, Juin P, Barillé-Nion S. γ-Secretase inhibition promotes cell death, Noxa upregulation, and sensitization to BH3 mimetic ABT-737 in human breast cancer cells. Breast Cancer Res. 2012 Jun 15;14(3):R96. PubMed PMID: 22703841; PubMed Central PMCID: PMC3446359.
纯度:≥98%
CAS:161710-10-7