Zankiren is a renin inhibitor. It can reduce blood pressure, plasma renin activity, and angiotension II. It can decrease blood pressure and circulating components of the RAS in normotensive volunteers as a result of documented absorption. References: Ménard J, Boger RS, Moyse DM, Guyene TT, Glassman HN, Kleinert HD. Dose-dependent effects of the renin inhibitor zankiren HCl after a single oral dose in mildly sodium-depleted normotensive subjects. Circulation. 1995 Jan 15;91(2):330-8. PubMed PMID: 7805235.
纯度:≥98%
CAS:138742-43-5