Vinthionine binds covalently to rat liver DNA, RNA and protein in vivo, but not in vitro. This amino acid is directly mutagenic in Salmonella typhimurium TA100 and TA1535; the mechanism of its metabolic activation in vivo in bacteria and liver is under study. References: Catcott KC, Yan J, Qu W, Wysocki VH, Zhou ZS. Identifying Unknown Enzyme-Substrate Pairs from the Cellular Milieu with Native Mass Spectrometry. Chembiochem. 2017 Apr 4;18(7):613-617. doi: 10.1002/cbic.201600634. Epub 2017 Mar 14. PubMed PMID: 28140508.
纯度:≥98%
CAS:70858-14-9