CAS NO: | 403646-00-4 |
规格: | ≥98% |
包装 | 价格(元) |
5mg | 电议 |
50mg | 电议 |
500mg | 电议 |
MC-205 is a new transcriptional up-regulator and a natural fungal metabolite with antiproliferative activity against cancer cell lines. Expression of the luciferase activity was activated ca. 2-, 4-, and 6-fold by 1, 10, and 100 microM TMC-205, respectively. TMC-205 activated the transcriptional activity in a manner dependent on the presence of the enhancer element of SV40 in its promoter region. References: Gao Y, Osman S, Koide K. Total Synthesis and Biological Studies of TMC-205 and Analogues as Anticancer Agents and Activators of SV40 Promoter. ACS Med Chem Lett. 2014 Jun 23;5(8):863-7. doi: 10.1021/ml500025p. eCollection 2014 Aug 14. PubMed PMID: 25147604; PubMed Central PMCID: PMC4137371.
纯度:≥98%
CAS:403646-00-4