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TMC-205
本产品不向个人销售,仅用作科学研究,不用于任何人体实验及非科研性质的动物实验。
CAS NO:403646-00-4
规格:≥98%
包装与价格:
包装价格(元)
5mg电议
50mg电议
500mg电议

产品介绍

MC-205 is a new transcriptional up-regulator and a natural fungal metabolite with antiproliferative activity against cancer cell lines. Expression of the luciferase activity was activated ca. 2-, 4-, and 6-fold by 1, 10, and 100 microM TMC-205, respectively. TMC-205 activated the transcriptional activity in a manner dependent on the presence of the enhancer element of SV40 in its promoter region. References: Gao Y, Osman S, Koide K. Total Synthesis and Biological Studies of TMC-205 and Analogues as Anticancer Agents and Activators of SV40 Promoter. ACS Med Chem Lett. 2014 Jun 23;5(8):863-7. doi: 10.1021/ml500025p. eCollection 2014 Aug 14. PubMed PMID: 25147604; PubMed Central PMCID: PMC4137371.

纯度:≥98%

CAS:403646-00-4