Uncarinic acid E (277751-61-8)具有抗癌活性,Uncarinic acid E 通过 p53 的积累诱导 HepG2 细胞凋亡,改变 Bax/Bcl-2 比率,并激活半胱天冬酶,导致线粒体释放细胞色素 c。
中文别名 | 壬酸E(,MSDS,熔点,溶解度) |
英文别名 | Uncarinic acid E;(4aS,6aR,6aR,6bR,8aR,10S,12aR,14bS)-10-hydroxy-6a-[[(E)-3-(4-hydroxyphenyl)prop-2-enoyl]oxymethyl]-2,2,6b,9,9,12a-hexamethyl-1,3,4,5,6,6a,7,8,8a,10,11,12,13,14b-tetradecahydropicene-4a-carboxylic acid |
CAS号 | 277751-61-8 |
SMILES | CC1(CCC2(CCC3(C(=CCC4C3(CCC5C4(CCC(C5(C)C)O)C)C)C2C1)COC(=O)C=CC6=CC=C(C=C6)O)C(=O)O)C |
Inchi | InChI=1S/C39H54O6/c1-34(2)19-20-38(33(43)44)21-22-39(24-45-32(42)14-9-25-7-10-26(40)11-8-25)27(28(38)23-34)12-13-30-36(5)17-16-31(41)35(3,4)29(36)15-18-37(30,39)6/h7-12,14,28-31,40-41H,13,15-24H2,1-6H3,(H,43,44)/b14-9+/t28-,29-,30+,31-,36-,37+,38-,39-/m0/s1 |
分子式 Formula | C39H54O6 |
分子量 Molecular Weight | 618.8g/mol |
储藏条件 Storage conditions | 4℃条件下存储,-4℃条件下存储更佳 |