UCCF-853 is an activator of the CFTR Cl- channel which may be useful for therapy of cystic fibrosis. References: Caci E, Folli C, Zegarra-Moran O, Ma T, Springsteel MF, Sammelson RE, Nantz MH, Kurth MJ, Verkman AS, Galietta LJ. CFTR activation in human bronchial epithelial cells by novel benzoflavone and benzimidazolone compounds. Am J Physiol Lung Cell Mol Physiol. 2003 Jul;285(1):L180-8. Epub 2003 Mar 21. PubMed PMID: 12651632.
纯度:≥98%
CAS:625458-06-2