Poloxime is a non-ATP-competitive Plk1 inhibitor. It acts by bocking pSer/pThr recognition. References: Yin Z, Song Y, Rehse PH. Thymoquinone blocks pSer/pThr recognition by Plk1 Polo-box domain as a phosphate mimic. ACS Chem Biol. 2013 Feb 15;8(2):303-8. doi: 10.1021/cb3004379. Epub 2012 Nov 12. PubMed PMID: 23135290.
纯度:≥98%
CAS:17302-61-3