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Tioxolone
本产品不向个人销售,仅用作科学研究,不用于任何人体实验及非科研性质的动物实验。
Tioxolone图片
CAS NO:4991-65-5
规格:≥98%
包装与价格:
包装价格(元)
1g电议
2g电议
5g电议
10g电议
25g电议
50g电议

产品介绍
理化性质和储存条件
Molecular Weight (MW)168.17
FormulaC7H4O3S
CAS No.4991-65-5
Storage-20℃ for 3 years in powder form
-80℃ for 2 years in solvent
Solubility (In vitro)DMSO: 34 mg/mL (202.2 mM)
Water: < 1 mg/mL
Ethanol: 34 mg/mL (202.17 mM)
SMILESO=C1OC2=CC(O)=CC=C2S1
SynonymsTioxolone; Thioxolone;
实验参考方法
In Vitro

In vitro activity: Tioxolone is reported to possess cytostatic, antipsoriatic, antibacterial and anti-mycotic properties. Tioxolone is also added to some cosmetics (e.g. hair shampoos and skin cleansers), due to claims for its oil-regulating and antibacterial properties. The three-dimensional framework of Tioxolone is further stabilized by π-π interactions between the oxathiolone and benzene rings in partially overlapping molecules.

In VivoTioxolone, a Benzoxathiol derivatives, has been used in the local therapy of psoriasis vulgaris and acne, and also reported to have anti-bacterial, anti-mycotic, and cytostatic properties.
Animal model
Formulation & Dosage
References

Acta Crystallogr C. 2004 Jun;60(Pt 6):o395-6; Exp Mol Med. 2011 May 31;43(5):313-21.