CAS NO: | 4991-65-5 |
规格: | ≥98% |
包装 | 价格(元) |
1g | 电议 |
2g | 电议 |
5g | 电议 |
10g | 电议 |
25g | 电议 |
50g | 电议 |
Molecular Weight (MW) | 168.17 |
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Formula | C7H4O3S |
CAS No. | 4991-65-5 |
Storage | -20℃ for 3 years in powder form |
-80℃ for 2 years in solvent | |
Solubility (In vitro) | DMSO: 34 mg/mL (202.2 mM) |
Water: < 1 mg/mL | |
Ethanol: 34 mg/mL (202.17 mM) | |
SMILES | O=C1OC2=CC(O)=CC=C2S1 |
Synonyms | Tioxolone; Thioxolone; |
In Vitro | In vitro activity: Tioxolone is reported to possess cytostatic, antipsoriatic, antibacterial and anti-mycotic properties. Tioxolone is also added to some cosmetics (e.g. hair shampoos and skin cleansers), due to claims for its oil-regulating and antibacterial properties. The three-dimensional framework of Tioxolone is further stabilized by π-π interactions between the oxathiolone and benzene rings in partially overlapping molecules. |
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In Vivo | Tioxolone, a Benzoxathiol derivatives, has been used in the local therapy of psoriasis vulgaris and acne, and also reported to have anti-bacterial, anti-mycotic, and cytostatic properties. |
Animal model | |
Formulation & Dosage | |
References | Acta Crystallogr C. 2004 Jun;60(Pt 6):o395-6; Exp Mol Med. 2011 May 31;43(5):313-21. |