PQIP is a potent inhibitor of both the unphosphorylated (basal) and phosphorylated (activated) states of the kinase IGF1R (IGF1RK). References: Kim WY, Prudkin L, Feng L, Kim ES, Hennessy B, Lee JS, Lee JJ, Glisson B, Lippman SM, Wistuba II, Hong WK, Lee HY. Epidermal growth factor receptor and K-Ras mutations and resistance of lung cancer to insulin-like growth factor 1 receptor tyrosine kinase inhibitors. Cancer. 2012 Aug 15;118(16):3993-4003. doi: 10.1002/cncr.26656. Epub 2012 Feb 22. Erratum in: Cancer. 2012 Dec 15;118(24):6301. PubMed PMID: 22359227; PubMed Central PMCID: PMC3674414.
纯度:≥98%