Licofelone (formerly ML-3000) is a dual COX/LOX inhibitor with IC50 of 0.21/0.18 μM, respectively, and has the potential for the treatment of osteoarthritis. Licofelone is both an analgesic and an anti-inflammatory. Inhibition of 5-LOX may reduce the gastrointestinal toxicity associated with other non-steroidal anti-inflammatory drugs, which only inhibit COX (cyclooxygenase). Licofelone inhibits cyclooxygenase (COX) and lipoxygenase (LOX) pathways of arachidonic acid metabolism prevent cancer development and induce apoptosis.

纯度：≥98%

CAS：156897-06-2