Phenoprolamine Hydrochloride, formerly known as DDPH, is an adrenergic α1 receptor antagonist potentially for the treatment of hypertension. Phenoprolamine Hydrochloride is potent antihypertensive, neuroprotective and cardioprotective effects. Phenoprolamine Hydrochloride inhibited CYP2D and CYP3A activities and down-regulated their protein expression and mRNA transcription. Phenoprolamine Hydrochloride can efficiently penetrate through blood brain barrier and inhibit the contraction of vascular smooth muscle in the brain. References: Zhao L, Hu J, Chang Q, Ke Q, Xu R, Gu S, Chen H, Zeng F. A simple and sensitive HPLC method for quantitation of low phenoprolamine hydrochloride concentrations in human plasma and its pharmacokinetic application. Biomed Chromatogr. 2008 Mar;22(3):333-8. PubMed PMID: 18059052.

纯度：≥98%

CAS：93933-71-2