Metesind, formerly known as AG-331; AG-341, is a thymidylate synthase inhibitor potentially for the treatment of brain cancer and solid tumours. References: Bram E, Ifergan I, Shafran A, Berman B, Jansen G, Assaraf YG. Mutant Gly482 and Thr482 ABCG2 mediate high-level resistance to lipophilic antifolates. Cancer Chemother Pharmacol. 2006 Dec;58(6):826-34. PubMed PMID: 16612649.
纯度:≥98%
CAS:138384-68-6