CAS NO: | 1187460-81-6 |
包装: | 50mg, 100mg, 250mg |
规格: | ≥98% |
PF-184 is a potent and selective IKK-2 inhibitor, demonstrating target-specific anti-inflammatory activities in cellular assays and following orally bioavailable and local delivery in an in vivo model of airway inflammation. References: Wakenhut F, Allan GA, Fish PV, Fray MJ, Harrison AC, McCoy R, Phillips SC, Ryckmans T, Stobie A, Westbrook D, Westbrook SL, Whitlock GA. N-[(3S)-Pyrrolidin-3-yl]benzamides as novel dual serotonin and noradrenaline reuptake inhibitors: impact of small structural modifications on P-gp recognition and CNS penetration. Bioorg Med Chem Lett. 2009 Sep 1;19(17):5078-81. doi: 10.1016/j.bmcl.2009.07.049. Epub 2009 Jul 31. Erratum in: Bioorg Med Chem Lett. 2010 Jan 15;20(2):772. Ryckmans, Thomas [added]. PubMed PMID: 19647430.
纯度:≥98%
CAS:1187460-81-6