Description: OTSSP167 sulfate (OTS167 HCl), the sulfate salt of OTSSP-167 (OTS-167), is an orally bioavailable inhibitor of MELK (maternal embryonic leucine zipper kinase) with IC50 of 0.41 nM. MELK may be a promising target for GC treatment.
References: Oncotarget. 2012 Dec;3(12):1629-40; Oncotarget. 2016 Feb 2;7(5):6266-80.
Related CAS#: 1431697-89-0 (free base)
Publications Citing Use of InvivoChem OTSSP167: Toxicology. 2022 Jun 24;153243. doi: 10.1016/j.tox.2022.153243.
纯度:≥98%