NSC-668394 is a small molecule ezrin inhibitor. NSC-668394 inhibits ezrin phosphorylation, ezrin-actin interaction and ezrin-mediated motility of osteosarcoma (OS) cells in culture. NSC-668394 displays a novel targeted therapy that directly inhibits ezrin protein as an approach to prevent tumor metastasis. References: Andharia N, Joseph A, Hayashi M, Okada M, Matsuda H. Involvement of intracellular transport in TREK-1c current run-up in 293T cells. Channels (Austin). 2017 May 4;11(3):224-235. doi: 10.1080/19336950.2017.1279368. Epub 2017 Jan 13. PubMed PMID: 28085542; PubMed Central PMCID: PMC5463894.
纯度:≥98%
CAS:382605-72-3