NSC47924 is a laminin receptor (LR) inhibitor. The laminin receptor (LR) is a non-integrin protein, which binds both laminin-1 of the extracellular matrix and prion proteins, that hold a central role in prion diseases. References: Sarnataro D, Pepe A, Altamura G, De Simone I, Pesapane A, Nitsch L, Montuori N, Lavecchia A, Zurzolo C. The 37/67 kDa laminin receptor (LR) inhibitor, NSC47924, affects 37/67 kDa LR cell surface localization and interaction with the cellular prion protein. Sci Rep. 2016 Apr 13;6:24457. doi: 10.1038/srep24457. PubMed PMID: 27071549; PubMed Central PMCID: PMC4829897.
纯度:≥98%
CAS:6638-24-0