NS3861 is an α3β2 full agonist and an α3β4 partial agonist. References: Gade AR, Kang M, Khan F, Grider JR, Damaj MI, Dewey WL, Akbarali HI. Enhanced Sensitivity of α3β4 Nicotinic Receptors in Enteric Neurons after Long-Term Morphine: Implication for Opioid-Induced Constipation. J Pharmacol Exp Ther. 2016 Jun;357(3):520-8. doi: 10.1124/jpet.116.233304. Epub 2016 Apr 11. PubMed PMID: 27068812; PubMed Central PMCID: PMC4885510.
纯度:≥98%
CAS:216853-60-0