Description: AT-1015 HCl is a novel, potent and selective 5-HT2A serotonin receptor antagonist that is known to impair platelet aggregation and vasoconstriction. It blocks vascular and platelet 5-HT2A receptors.
References: Komiyama T, Kihara H, Hirose K, Yoshimoto R, Shigematsu H. AT-1015, a novel serotonin2A receptor antagonist, improves resaturation of exercised ischemic muscle in hypercholesterolemic rabbits. J Vasc Surg. 2004 Mar;39(3):661-7.