NIC is an inhibitor of host invasion. It acts by targeting malaria merozoite surface protein-1 (MSP-1). It is also an inhibitor of VEGF binding to immobilized heparin. References: Liu X, Lu L, Liu X, Pan C, Feng E, Wang D, Zhu L, Wang H. Comparative proteomics of Shigella flexneri 2a strain 301 using a rabbit ileal loop model reveals key proteins for bacterial adaptation in host niches. Int J Infect Dis. 2015 Nov;40:28-33. doi: 10.1016/j.ijid.2015.09.014. Epub 2015 Sep 28. PubMed PMID: 26417879.
纯度:≥98%
CAS:114773-20-5