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Nexinhib20
本产品不向个人销售,仅用作科学研究,不用于任何人体实验及非科研性质的动物实验。
Nexinhib20图片
CAS NO:331949-35-0
规格:≥98%
包装与价格:
包装价格(元)
10mg电议
25mg电议
50mg电议

产品介绍
Nexinhib20 (neutrophil exocytosis inhibitor 20) is a novel and potent protein-protein interaction inhibitor, inhibiting the interaction between the small GTPase Rab27a and its effector JFC1
(synaptotagmin-like protein1). Nexinhib20 inhibits exocytosis of
azurophilic granules in human neutrophils without affecting other
important innate immune responses including phagocytosis and neutrophil
extracellular trap production. Nexinhib20 prevents the expression of cytochrome b558 in the plasma membrane. It modulates vesicular trafficking and neutrophil activities. Nexinhib20 reduces the systemic inflammation, mediated by neutrophils.