MU-380 is a potent and selective CHK1 inhibitor. References: Samadder P, Suchánková T, Hylse O, Khirsariya P, Nikulenkov F, Drápela S, Straková N, Vaňhara P, Vasícková K, Kolárová H, Binó L, Bittová M, Ovesná P, Kollár P, Fedr R, Esner M, Jaros J, Hampl A, Krejcí L, Paruch K, Soucek K. Synthesis and Profiling of a Novel Potent Selective Inhibitor of CHK1 Kinase Possessing Unusual N-trifluoromethylpyrazole Pharmacophore Resistant to Metabolic N-dealkylation. Mol Cancer Ther. 2017 Sep;16(9):1831-1842. doi: 10.1158/1535-7163.MCT-17-0018. Epub 2017 Jun 15. PubMed PMID: 28619751.
纯度:≥98%
CAS:2109805-78-7