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BCM-599
本产品不向个人销售,仅用作科学研究,不用于任何人体实验及非科研性质的动物实验。
CAS NO:1820763-99-2
规格:≥98%
包装与价格:
包装价格(元)
5mg电议
50mg电议
500mg电议

产品介绍

BCM-599 is a HBV capsid assembly inhibitor. BCM-599 could be utilized as an effective combination treatment against HBV infection. BCM-599 showed IC50 of 0.88 μM and CC50 of 144 μM in HepG2.2.15 cells. BCM-599 decreased both intracellular and extracellular viral DNA levels without affecting the pgRNA level; moreover, interestingly, at the concentration of 0.88 μM, BCM-599 reduced the intracellular capsid level by 51% while increased the amount of free core protein dimer by 5-fold. References: Cho MH, Jeong H, Kim YS, Kim JW, Jung G. 2-amino-N-(2,6-dichloropyridin-3-yl)acetamide derivatives as a novel class of HBV capsid assembly inhibitor. J Viral Hepat. 2014 Dec;21(12):843-52. doi: 10.1111/jvh.12214. Epub 2013 Dec 25. PubMed PMID: 24372792.

纯度:≥98%

CAS:1820763-99-2