ABBV-744是一种对BDII具有选择性的BET bromodomain抑制剂，可抑制BRD2、BRD3和BRD4。它可进一步研究用于治疗急性髓细胞性白血病和癌症。

CAS：2138861-99-9
分子式：C28H30FN3O4
分子量：491.55
纯度：＞99%
存储：Store at -20°C

Background:

ABBV-744 is a BDII-selective BET bromodomain inhibitor that is being investigated to treat AML and metastic castration-resistant prostate cancer.

Reference：

[1]. FIDANZE, Steven D., et al. BROMODOMAIN INHIBITORS. WO 2017177955 A1.

HNMR检测如下图：