AMG-510(Sotorasib)racemate
A KRAS G12C covalent inhibitor
CAS:2252403-56-6
分子式:C30H30F2N6O3
分子量:560.59
纯度:98%
存储:Store at -20°C
Background:
AMG-510 racemate is the racemate of AMG-510. AMG-510 is a potent, orally bioavailable, and selective KRAS G12C covalent inhibitor with anti-tumor activity.
参考文献:
[1]. Karen Rex, et al. Abstract 3090: In vivo characterization of AMG 510 - a potent and selective KRASG12Ccovalent small molecule inhibitor in preclinical KRASG12Ccancer models. Experimental and Molecular Therapeutics.