Propyphenazone是一种吡唑啉酮衍生物,具有消炎、止痛和解热活性的。Propyphenazone为基础的类似物通常作为前药,选择性抑制环氧合酶-2(COX-2)。
CAS:479-92-5
分子式:C14H18N2O
分子量:230.31
纯度:98%
存储:Store at -20°C
Background:
Propyphenazone is a pyrazolone derivative with anti-inflammatory, analgesic and antipyretic activity, Propyphenazone-based analogues as prodrugs and selective cyclooxygenase-2 inhibitors.Target:COX-2Propyphenazone is structurally related to aminophenazone it has been associated with severe blood dyscrasias. Propyphenazone is introduced for the treatment of rheumatic disorders.
[1]. Burdan F, et al. Formation of the knee joint after prenatal propyphenazone (isopropylantipyrine) administration. Cells Tissues Organs. 2002;171(2-3):145-51.