GSK-3β inhibitor 1 (compound 3a) 是糖原合成酶激酶 3β (GSK-3β)的抑制剂，具有治疗糖尿病的潜能，其对 GSK-3β 的 IC50 值为 4.9 nM。
CAS：187325-53-7
分子式：C14H10N2O
分子量：222.24
纯度：98%
存储：Store at -20°C

Background:

GSK-3β inhibitor 1 (compound 3a) is a glycogen synthase kinase 3β (GSK-3β) inhibitor and demonstrates high antidiabetic efficacy, with an IC50 of 4.9 nM[1]. GSK-3β|4.9 nM (IC50)

[1]. Lozinskaya NA, et al. Synthesis and biological evaluation of 3-substituted 2-oxindole derivatives as new glycogen synthase kinase 3β inhibitors. Bioorg Med Chem. 2019 May 1;27(9):1804-1817.