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Tropodifene(Tropaphen)
本产品不向个人销售,仅用作科学研究,不用于任何人体实验及非科研性质的动物实验。
Tropodifene(Tropaphen)图片
CAS NO:15790-02-0
规格:98%
分子量:407.5
包装与价格:
包装价格(元)
1mg电议
5mg电议
10mg电议
20mg电议

产品介绍
Tropodifene(Tropaphen)是α-肾上腺素能受体(α-Adrenergicreceptor)抑制剂。
CAS:15790-02-0
分子式:C25H29NO4
分子量:407.5
纯度:98%
存储:Store at -20°C

Background:

Tropodifene (Tropaphen) is an α-Adrenergic receptor inhibitor.



Tropaphen has a beneficial effect on hypertension. The therapeutic effect of this preparation is more constant in diseases accompanied by spasm of the peripheral vessels. Tropaphen has a very marked adrenolytic and vasodilator action. It greatly lowers the tone of the peripheral vessels. The preparation is effective starting with a dose of 0.1 mg/kg. After injection of the drug in a dose of 0.25 mg/kg, a considerable and gradually progressive decrease in the perfusion pressure takes place. The pressure falls by 30-35% and remained at a low level for 90-100 min. With a dose of tropaphen of 0.5 mg/kg, the perfusion pressure falls by 40-45% and remains low for 120 min or more. Strong vasodilatation is also observed after injection of tropaphen into intact rabbits[1].


[1]. Mashkovskii MD, et al. The action of tropaphen on the peripheral vessels. Pharmacology. 1964. 58. 69-71.