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CK 666
本产品不向个人销售,仅用作科学研究,不用于任何人体实验及非科研性质的动物实验。
CK 666图片
CAS NO:442633-00-3
规格:98%
分子量:296.34
包装与价格:
包装价格(元)
10mg电议
50mg电议

产品介绍
Arp2/3 complex inhibitor that inhibits actin polymerization
CAS:442633-00-3
分子式:C18H17FN2O
分子量:296.34
纯度:98%
存储:Store at -20°C

Background:

CK-666 is a cell-permeable inhibitor of actin-related protein Arp2/3 complex, and binds to Arp2/3 complex, stabilizes the inactive state of the complex, blocking movement of the Arp2 and Arp3 subunits into the activated filament-like (short pitch) conformation[1].


参考文献:
[1]. Hetrick B, et al. Small molecules CK-666 and CK-869 inhibit actin-related protein 2/3 complex by blocking an activating conformational change. Chem Biol. 2013 May 23;20(5):701-12.