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EML4-ALK kinase inhibitor 1
本产品不向个人销售,仅用作科学研究,不用于任何人体实验及非科研性质的动物实验。
EML4-ALK kinase inhibitor 1图片
CAS NO:1373409-08-5
规格:98%
分子量:580.76
包装与价格:
包装价格(元)
250mg电议
500mg电议

产品介绍
EML4-ALK kinase inhibitor 1 是有效的、具有口服活性的类棘皮细胞微管相关蛋白4-间变性淋巴瘤激酶 (EML4-ALK) 的抑制剂,其 IC50 值为 1 nM。
CAS:1373409-08-5
分子式:C31H48N8O3
分子量:580.76
纯度:98%
存储:Store at -20°C

Background:

EML4-ALK kinase inhibitor 1 is a potent oral active inhibitor of echinoderm microtubule-associated protein-like 4-anaplastic lymphoma kinase (EML4-ALK), with an IC50 of 1 nM[1]. IC50: 1 nM (EML4-ALK)[1].




[1]. Iikubo K, et al. Synthesis and structure-activity relationships of pyrazine-2-carboxamide derivatives as novel echinoderm microtubule-associated protein-like 4 (EML4)-anaplastic lymphoma kinase (ALK) inhibitors. Bioorg Med Chem. 2019 Apr 15;27(8):1683-1692.