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KS 176
本产品不向个人销售,仅用作科学研究,不用于任何人体实验及非科研性质的动物实验。
KS 176图片
CAS NO:1253452-78-6
规格:98%
分子量:405.4
包装与价格:
包装价格(元)
10mg电议
50mg电议

产品介绍
inhibitor of the breast cancer resistance protein (BCRP) multidrug transporter
CAS:1253452-78-6
分子式:C22H19N3O5
分子量:405.4
纯度:98%
存储:Store at -20°C

Background:

KS176 is a potent and selective inhibitor of the breast cancer resistance protein (BCRP) multidrug transporter (IC50 values are 0.59 and 1.39 μM in Pheo A and Hoechst 33342 assays respectively). Displays no inhibitory activity against P-gp or MRP1.IC50 value: 0.59( in Pheo A assay), 1.39 μM (in Hoechst 33342 assay).Target: BCRPThe more detailed information please refer to Compound 9 in the reference.


参考文献:
[1]. Pick A, et al. Specific inhibitors of the breast cancer resistance protein (BCRP). ChemMedChem. 2010 Sep 3;5(9):1498-505.