CAS NO: | 1303420-67-8 |
包装: | 5mg |
规格: | 98% |
市场价: | 750元 |
分子量: | 395.41 |
Background:
PLX5622 is a highly selective brain penetrant and oral active CSF1R inhibitor, for extended and specific microglial elimination, preceding and during pathology development. PLX5622 demonstrates desirable PK properties in varies animals[1]. CSF1R[1].
[1]. Spangenberg E, et al. Sustained microglial depletion with CSF1R inhibitor impairs parenchymal plaque development in an Alzheimer’s disease model. Nat Commun. 2019 Aug 21;10(1):3758.