SIRT5inhibitor是人类Sirtuin5脱酰酶的抑制剂,其IC50值为0.11μM。
CAS:2166487-21-2
分子式:C31H39FN6O6S2
分子量:674.81
纯度:98%
存储:Store at -20°C
Background:
SIRT5 inhibitor is a potent Human Sirtuin 5 deacylase inhibitor, with an IC50 of 0.11 μM.
SIRT5 inhibitor (compound 49) is a very potent Human Sirtuin 5 deacylase inhibitor, with an IC50 of 0.11 μM, >100-fold from compound 1[1].
[1]. Rajabi N, et al. Mechanism-Based Inhibitors of the Human Sirtuin 5 Deacylase: Structure-Activity Relationship, Biostructural, and Kinetic Insight. Angew Chem Int Ed Engl. 2017 Nov 20;56(47):14836-14841.