p38-αMAPK-IN-1是MAPK14(p38-α)抑制剂，在EFC和HTRF实验中，IC50值分别为2300nM和5500nM。
CAS：443913-15-3
分子式：C27H35N5O3
分子量：477.6
纯度：98%
存储：Store at -20°C

Background:

p38-α MAPK-IN-1 is an inhibitor of MAPK14 (p38-α), with IC50 of 2300 nM in EFC displacement assay, and 5500 nM in HTRF assay.

p38-α MAPK-IN-1 (Compound 12) is an inhibitor of MAPK14 (p38-α)>, with IC50 of 2300 nM in EFC displacement assay, and 5500 nM in HTRF assay[1].

[1]. Kluter S, et al. Displacement assay for the detection of stabilizers of inactive kinase conformations. J Med Chem. 2010 Jan 14;53(1):357-67.