Angiotensin II (3-8), human 是一种活性稍弱的血管紧张素 AT1 受体激动剂。
CAS：12676-15-2
分子式：C40H54N8O8
分子量：774.91
纯度：98%
存储：Store at -20°C

Background:

Angiotensin II (3-8), human is a less effective agonist at the angiotensin AT1 receptor. Angiotensin AT1 receptor[1]

Human Angiotensin II (3-8) causes endothelium-dependent renal cortical vasodilatation, in anaesthetized rats. At doses up to 125 pmol/kg, human Angiotensin II (3-8) is without any cardiovascular effects, but with doses of 1.25 and 12.5 nmol/kg there are dose-dependent increases in mean arterial blood pressure and reductions in renal and mesenteric flows and vascular conductances[1].

[1]. Gardiner SM, et al. Regional haemodynamic effects of angiotensin II (3-8) in conscious rats. Br J Pharmacol. 1993 Sep;110(1):159-62.