sarco-endoplasmic reticulum Ca2+-ATPases inhibitor
CAS：67526-95-8
分子式：C34H50O12
分子量：650.76
纯度：98%
存储：Store at -20°C

Background:

In cells, sarco/endoplasmic calcium ATPases (SERCAs) transport free calcium into the sarcoplasmic and endoplasmic reticula, lowering intracellular calcium levels to stop signaling through this cation. Thapsigargin is a non-competitive, cell permeable inhibitor of calcium transport by SERCAs (IC₅₀values are cell type-dependent and range from