1,4-Chrysenequinone(Chrysene-1,4-dione)是一种多环芳香烃类,可以作为芳香烃受体(AhR)的激活剂起作用。
CAS:100900-16-1
分子式:C18H10O2
分子量:258.27
纯度:98%
存储:Store at -20°C
Background:
1,4-Chrysenequinone (Chrysene-1,4-dione), a polycyclic aromatic quinone, acts as an activator of aryl hydrocarbon receptor (AhR).
1,4-Chrysenequinone shows significant AhR ligand activity, with ECTCDD25s (concentration equivalent with 25% of TCDD max) of 9.7 nM and 1.9 μM in yeast and mouse hepatoma cell systems, respectively[1].
[1]. Misaki K, et al. Aryl hydrocarbon receptor ligand activity of polycyclic aromatic ketones and polycyclic aromatic quinones. Environ Toxicol Chem. 2007 Jul;26(7):1370-9.