Imirestat(AL1576)是一种aldosereductase抑制剂，可用于治疗糖尿病。
CAS：89391-50-4
分子式：C15H8F2N2O2
分子量：286.23
纯度：98%
存储：Store at -20°C

Background:

Imirestat (AL 1576) is an aldose reductase inhibitor, used for the treatment of diabetes.

Imirestat (1 mg/kg) improves nerve conduction velocity but is without effect upon the resistance to hypoxic conduction blockade or the deficit in insulin-stimulated oubain-sensitive ATPase activity[1].

[1]. Carrington AL, et al. Aldose reductase inhibition with imirestat-effects on impulse conduction and insulin-stimulation of Na+/K(+)-adenosine triphosphatase activity in sciatic nerves of streptozotocin-diabetic rats. Diabetologia. 1991 Jun;34(6):397-401.