CAS NO: | 68506-86-5 |
规格: | 98% |
分子量: | 129.16 |
包装 | 价格(元) |
200mg | 电议 |
500mg | 电议 |
5mg | 电议 |
50mg | 电议 |
100mg | 电议 |
Background:
Vigabatrin is a structural analog of the inhibitory neurotransmitter γ-aminobutyric acid (GABA) that irreversibly inhibits the catabolism of GABA by GABA transaminase.[1] It produces a dose-dependent increase in extracellular GABA, and has been shown to result in increasing seizure suppression.[2]
Reference:
[1]. Willmore, L.J., Abelson, M.B., Ben-Menachem, E., et al. Vigabatrin: 2008 Update. Epilepsia 50(2), 163-173 (2009).
[2]. Appleton, R.E. The new antiepileptic drugs. Arch. Dis. Child. 75(3), 256-262 (1996).