The Aurora kinases are a family of serine/threonine kinases that are key regulators of mitosis and cytokinesis.
CAS:331770-21-9
分子式:C23H20N4O3
分子量:400.4
纯度:98%
存储:Store at -20°C
Background:
The Aurora kinases are a family of serine/threonine kinases that are key regulators of mitosis and cytokinesis. Aurora kinase inhibitor II is a cell-permeable anilinoquinazoline that blocks the activity of Aurora A (IC50 = 0.39 µM). In MCF-7 cells, it blocks proliferation with an IC50 value of 1.25 µM.