BNC375 是一种口服有效的选择性 α7nAChRs I 型正向变构调节剂,EC50 为 1.9 μM。
CAS:1557240-80-8
分子式:C19H23ClN2O3S
分子量:394.92
纯度:98%
存储:Store at -20°C
Background:
BNC375 is a potent, selective, and orally available type I positive allosteric modulator of α7 nAChRs with an EC50 of 1.9 μM[1].
[1]. Andrew J. Harvey, et al. Discovery of BNC375, a Potent, Selective, and Orally Available Type I Positive Allosteric Modulator of α7 nAChRs. Cite This:ACS Med. Chem. Lett.2019105754-760.