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Isoastragaloside I(Isoastragaloside-I)
本产品不向个人销售,仅用作科学研究,不用于任何人体实验及非科研性质的动物实验。
Isoastragaloside I(Isoastragaloside-I)图片
CAS NO:84676-88-0
规格:98%
分子量:869.04
包装与价格:
包装价格(元)
5mg电议
10mg电议

产品介绍
异黄芪皂苷I(IsoastragalosideI)是中药黄芪的一种天然化合物,具有提高脂联素量活性。
CAS:84676-88-0
分子式:C45H72O16
分子量:869.04
纯度:98%
存储:Store at -20°C

Background:

Isoastragaloside I is a natural compound from the medicinal herb Radix Astragali; possesses the activity of elevating adiponectin production.IC50 value:Target:Astragaloside II and isoastragaloside I selectively increased adiponectin secretion in primary adipocytes without any obvious effects on a panel of other adipokines. Furthermore, an additive effect on induction of adiponectin production was observed between these two compounds and rosiglitazone, a thiazolidinedione class of insulin-sensitizing drugs. Chronic administration of astragaloside II and isoastragaloside I in both dietary and genetic obese mice significantly elevated serum levels of total adiponectin and selectively increased the composition of its high molecular weight oligomeric complex.




[1]. Xu A, et al. Selective elevation of adiponectin production by the natural compounds derived from a medicinal herb alleviates insulin resistance and glucose intolerance in obese mice. Endocrinology. 2009 Feb;150(2):625-33.