Acecainide is an active metabolite of the class III antiarrhythmic procainamide.
CAS:34118-92-8
分子式:C15H23N3O2.HCl
分子量:313.8
纯度:98%
存储:Store at -20°C
Background:
Acecainide is an active metabolite of the class III antiarrhythmic procainamide. It is formed from procainamide via hepatic N-acetyltransferases. Acecainide prevents hypoxia-induced ventricular fibrillation in mice and decreases arrhythmia induced by aconitine in dogs. Acecainide (10 µM), when used in high-fat medium, decreases lipid droplet area by greater than 50% in SK-Hep1 cells without inducing cytotoxicity but does not affect lipid droplets in primary mouse hepatocytes.