Wilforgine 是 Tripterygium wilfordii Hook. F 中的生物活性倍半萜烯生物碱。Wilforgine 能诱导分离出丝状体幼虫肌肉的微结构和超微结构变化，其作用部位被认为是肌肉系统中的钙受体或通道。
CAS：37239-47-7
分子式：C41H47NO19
分子量：857.81
纯度：98%
存储：Store at -20°C

Background:

Wilforgine is a bioactive sesquiterpene alkaloid in Tripterygium wilfordii Hook. F. Wilforgine can induce microstructural and ultrastructural changes in the muscles of Mythimna separata larvae, and the sites of action are proposed to be calcium receptors or channels in the muscular system[1][2].

[1]. Ouyang XK, et al. Simultaneous determination of four sesquiterpene alkaloids in Tripterygium wilfordii Hook. F. extracts by high-performance liquid chromatography. Phytochem Anal. 2007 Jul-Aug;18(4):320-5. [2]. Ma S, et al. Comparative studies on muscle microstructure and ultrastructure of Mythimna separata Walker treated with wilforgine and chlorantraniliprole. Ecotoxicol Environ Saf. 2018 Jan;147:1023-1034. [3]. Gao X, et al. Wilforine, the Q-marker and PK-maker of Tripterygium glycosides tablet: Based on preparation quantitative analysis and PK-PD study. Phytomedicine. 2019 Feb 15;54:357-364.