CK1-IN-1是一种酪蛋白激酶1(CK1)抑制剂,对CK1δ、CK1ε、p38σMAPK的IC50值为15nM,16nM,73nM,详细信息请参考专利WO2015119579A1,化合物1c。
CAS:1784751-20-7
分子式:C24H15F2N3
分子量:383.39
纯度:98%
存储:Store at -20°C
Background:
CK1-IN-1 is a casein kinase 1 (CK1) inhibitor extracted from patent WO2015119579A1, compound 1c, has IC50s of 15 nM, 16 nM, 73 nM for CK1δ, and CK1ε, p38σ MAPK, respectively[1].
CKIδ|15 nM (IC50)|CK1?|16 nM (IC50)
[1]. Filip LACO,et al. 2,4,5-tri-substituted azole-based casein kinase 1 inhibitors as inducers for cardiomyogenesis. WO2015119579A1.