GPR35 agonist 1 (compound 50)是一种高效特异性的 GPR35/CXCR8 激动剂，EC50 值为 5.8 nM，具有很好的成药性。
CAS：2079880-92-3
分子式：C10H4BrN5O5
分子量：354.07
纯度：98%
存储：Store at -20°C

Background:

GPR35 agonist 1 (compound 50) is a potent and specific G protein-coupled receptor-35 (GPR35)/CXCR8 agonist with an EC50 of 5.8 nM, displays good druggability[1]. CXCR8|5.8 nM (EC50)

[1]. Wei L, et al. Discovery of 2H-Chromen-2-one Derivatives as G Protein-Coupled Receptor-35 Agonists. J Med Chem. 2017 Jan 12;60(1):362-372.