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Syntide 2
本产品不向个人销售,仅用作科学研究,不用于任何人体实验及非科研性质的动物实验。
CAS NO:108334-68-5
规格:98%
分子量:1507.82
包装与价格:
包装价格(元)
1mg电议
5mg电议
10mg电议

产品介绍
Syntide2是可被Ca2+/钙调蛋白依赖性蛋白激酶II(CaMKII)识别的底物。
CAS:108334-68-5
分子式:C68H122N20O18
分子量:1507.82
纯度:98%
存储:Store at -20°C

Background:

Syntide 2 is recognized as a substrate by Ca2+/calmodulin-dependent protein kinase II (CaMKII) with a Ki of 12 μM.


The sequence of syntide-2 (pro-leu-ala-arg-thr-leu-ser-val-ala-gly-leu-pro-gly-lys-lys) is homologous to phosphorylation site 2 in glycogen synthase. The relative Vmax/Km ratios of the known Ca2+-dependent protein kinases for syntide-2 are determined to be as follows: protein kinase II, 100; protein kinase C, 22; phosphorylase kinase, 2; myosin light chain kinase, 0.005[1].



[1]. Hashimoto Y, et al. Calcium . calmodulin-dependent protein kinase II and calcium . phospholipid-dependent protein kinase activities in rat tissues assayed with a synthetic peptide. Arch Biochem Biophys. 1987 Feb 1;252(2):418-25.